About Help FAQ

Symbol
Name
ID

Hfe
homeostatic iron regulator
MGI:109191

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Cerebral hemorrhage	Spinal cord compression	Depression	Irritability	Anxiety	Apathy	Lethargy	Addictive alcohol use	Peripheral neuropathy	Paresthesia
Disease(s) Associated with HFE	Cerebral hemorrhage	Spinal cord compression	Depression	Irritability	Anxiety	Apathy	Lethargy	Addictive alcohol use	Peripheral neuropathy	Paresthesia
beta thalassemia
cystic fibrosis
hemochromatosis type 1
multiple myeloma
polycythemia vera
porphyria cutanea tarda

Mouse Phenotypes		abnormal brain iron level	decreased brain cholesterol level	abnormal brain size	decreased brain weight	enlarged brain ventricles	decreased corpus callosum size	astrocytosis	neuron degeneration
Availability	Mouse Genotype	abnormal brain iron level	decreased brain cholesterol level	abnormal brain size	decreased brain weight	enlarged brain ventricles	decreased corpus callosum size	astrocytosis	neuron degeneration
	Hfe^tm1.1Jrco/Hfe^tm1.1Jrco
	Hfe^tm2Sly/Hfe^tm2Sly

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23